|Born||3 February 1921|
|Died||28 November 2012|
|Political party||Botswana Independence Party|
|Spouse(s)||Onalepelo Hannah Macheng|
Motsamai Keyecwe Mpho (February 3, 1921 – November 28, 2012) was a Motswana activist and politician. He founded Botswana's first political party in 1960, the Botswana People's Party, then known as the Bechualand People's Party, alongside Klaas Motshidisi, Kgalemang Motsete, and Philip Matante. However, due to conflict within the party, Mpho left and founded the Botswana Independence Party in 1964. He also served as a member of the National Assembly. Some historians believe that Mpho was the first to introduce the term 'Botswana' into formal political vocabulary, replacing the colonialist name of Bechuanaland.
- Presidential Award for Meritorious Service (Government of Botswana)
- Order of the Companions of O. R. Tambo (Government of South Africa, 26 April 2005)
- Morton, Fred; Ramsay, Jeff; Mgadla, Part Themba (2008). Historical Dictionary of Botswana (4th ed.). Lanham, Md.: Scarecrow Press. p. 148. ISBN 0810854678.
- "Mmegi Online :: Motsamai Mpho turns 90". Mmegi Online. Retrieved 2018-01-14.
- "Motsamai Keyecwe Mpho (1921 - ) | The Presidency". www.thepresidency.gov.za. Retrieved 2018-01-14.
- "MOTSAMAI MPHO DIES | TheVoiceBW". thevoicebw.com. Retrieved 2018-01-14.
- "Motsamai Mpho Dies". The Voice. 1 December 2012. Retrieved 29 September 2016.